[peptideismylife]

Hey,

I have no experience with this instrument. I heard that it really useful to remove water trace of your product...

Do you know how it works and what is it for?

[Oxime]

Lyophilizers are used to freeze-dry desired compounds. In the case of peptides, this usually means HPLC eluent containing your product. Desired fractions are frozen in dry ice and then lyophilized to dryness over the course of 1-2 days.

As far as solvents, acetonitrile and water are both safe to use on a lyophilizer; however, it needs to be less than ~30% by volume acetonitrile to remain frozen while lyophilizing. Methanol and other HPLC solvents are often not compatible with lyophilization; I suppose at that point it would depend on what type of lyophilizer you have. Before using a particular solvent, be sure that it is safe to use - if organic solvent gets into the vacuum pump for the lyophilizer, it can be difficult/expensive to fix.