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HPLC

Separation
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Mobile Phase
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Voting closed: August 24, 2011, 06:30:25 AM

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Topic: sodium lauryl sulfate  (Read 3492 times)

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Offline Ravinder

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sodium lauryl sulfate
« on: August 17, 2011, 06:30:25 AM »
How the sodium lauryl sulfate effects the separation in the HPLC mobile phase
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Offline Pradeep

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Re: sodium lauryl sulfate
« Reply #1 on: August 22, 2011, 10:11:49 AM »
SLS is an anionic surfactant. Its a linear organic compound. Therefore it can cover the stationary phase of a reverse phase  column.  Then it will form monolayers and the separation will be collapsed.
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Offline Train

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Re: sodium lauryl sulfate
« Reply #2 on: August 22, 2011, 09:50:32 PM »
It can improve the retention of cationic compounds.
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