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Topic: can guanidine hydrochloride derivatives react with isocyanate ?  (Read 3381 times)

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Offline yxw1987

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can guanidine hydrochloride derivatives react with isocyanate ?
« on: October 18, 2011, 10:12:49 AM »
it's well known that the isocyanates can react with compounds containing active hydrogen, I want to know whether the isocyanates react with guanidine hydrochloride derivatives? ???

Offline Honclbrif

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Re: can guanidine hydrochloride derivatives react with isocyanate ?
« Reply #1 on: October 18, 2011, 11:11:52 AM »
Yes they can
Individual results may vary

Offline sjb

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Re: can guanidine hydrochloride derivatives react with isocyanate ?
« Reply #2 on: October 18, 2011, 12:45:28 PM »
it's well known that the isocyanates can react with compounds containing active hydrogen, I want to know whether the isocyanates react with guanidine hydrochloride derivatives? ???

I would imagine that the isocyanate would probably react with HCl to liberate carbon dioxide and the ammonium salt, if the reaction were not kept dry. However, if it were, then perhaps it's possible - do you have access to something like Scifinder or similar?

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