Can you provide structural information? Did you use methanol? From my experience, DMA (N,N-Dimethylacetamide) is one of the best solvents for debenzylation of amines. Some amines tend to deactivate the palladium catalyst via complexation. DMA will prevent this.
Thank you for this tip! I used DMA to debenzylate a pyrrolidine derivative. Worked like magic at RT and 1atm of hydrogen. It's so important to be able to use benzyl as a protecting group instead of Cbz, since it keeps the nitrogen nucleophilic.