March 03, 2024, 05:15:49 AM
Forum Rules: Read This Before Posting


Topic: What is "Florisil" used for in Chemistry experiment ?  (Read 34825 times)

0 Members and 1 Guest are viewing this topic.

Offline caphyboy

  • Regular Member
  • ***
  • Posts: 12
  • Mole Snacks: +0/-0
What is "Florisil" used for in Chemistry experiment ?
« on: August 18, 2006, 09:20:56 AM »
   
        At present, I read a paper which mentions  Florisil in the course of a experiment. But I don not know Florisil before.And now, I am eager to know througly what on earth Florisil is.

      Would you help me ,please?

       Thanks!

Offline Albert

  • Lonely Wanderer
  • Retired Staff
  • Sr. Member
  • *
  • Posts: 1050
  • Mole Snacks: +112/-22
  • Gender: Male
  • Half Decent Pharmaceutical Chemist

Offline movies

  • Organic Minion
  • Retired Staff
  • Sr. Member
  • *
  • Posts: 1973
  • Mole Snacks: +222/-21
  • Gender: Male
  • Better living through chemistry!
Re: What is "Florisil" used for in Chemistry experiment ?
« Reply #2 on: August 18, 2006, 11:55:36 AM »
Florisil is a nice alternative for chromatography because it is less polar and less acidic than silica gel (SiO2).  Alumina is another alternative and its polarity falls between silica gel and florisil.

Due to its low polarity it is useful for very polar compounds which would "stick" too strongly to silica gel.  Its also good for very non-polar compounds that just fly off a silica gel column.

Offline caphyboy

  • Regular Member
  • ***
  • Posts: 12
  • Mole Snacks: +0/-0
Re: What is "Florisil" used for in Chemistry experiment ?
« Reply #3 on: August 18, 2006, 10:09:10 PM »
First, I must give my thanks to Albert and  movies.Thank you !

Offline VMPRH

  • Very New Member
  • *
  • Posts: 1
  • Mole Snacks: +0/-0
Re: What is "Florisil" used for in Chemistry experiment ?
« Reply #4 on: January 12, 2012, 11:57:38 AM »
Does anybody know how to recover the Florisil compound in order to use one more time and also to save money?
Thank you a lot!!


Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +405/-70
  • Gender: Male
    • My research history
Re: What is "Florisil" used for in Chemistry experiment ?
« Reply #5 on: January 12, 2012, 02:57:24 PM »
Does anybody know how to recover the Florisil compound in order to use one more time and also to save money?
Thank you a lot!!



Just wash it several times with a polar solvent, methanol.
Check the last MeOH wash for impurities (HPLC), then equilibrate it with your elution solvent.
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Sponsored Links