July 05, 2020, 06:41:59 AM
Forum Rules: Read This Before Posting


Topic: Problem of the week 14/01/12  (Read 8774 times)

0 Members and 1 Guest are viewing this topic.

Offline azmanam

  • Chemist
  • Sr. Member
  • *
  • Posts: 1417
  • Mole Snacks: +160/-24
  • Mediocrity is a handrail -Charles Louis d'Secondat
Re: Problem of the week 14/01/12
« Reply #15 on: January 18, 2012, 04:39:15 PM »
Nice.  I thought about a second lactone opening pathway, but saw the 5-endo and went intermolecular.  I didn't think about epoxide 7.
Knowing why you got a question wrong is better than knowing that you got a question right.

Offline Honclbrif

  • Chemist
  • Full Member
  • *
  • Posts: 659
  • Mole Snacks: +58/-10
  • Gender: Male
Re: Problem of the week 14/01/12
« Reply #16 on: January 18, 2012, 10:17:39 PM »
I always screw up the endo/exo thing when it comes to epoxides and was messing around with 4 in acid. I do not know where to hide my face.

Congrats to azmanam on solving this one. I tip my hat, sir.

I must say Dan, this was a fine problem, even though some parts were a serious Payne. I look forward to tackling future POTWs.
Individual results may vary

Offline Guitarmaniac86

  • Full Member
  • ****
  • Posts: 206
  • Mole Snacks: +19/-2
  • Synthetic Organic/Medicinal Chemist
Re: Problem of the week 14/01/12
« Reply #17 on: January 23, 2012, 04:25:24 PM »
This is the kind of thing the post grads do with the lecturers at my uni. Every week we try and crack a synthesis from a paper that has been published. Who ever cracks the synthesis gets to find a paper with an interesting synthesis.

However, I didnt get this at all.

Sponsored Links