Since I have been doing my Masters, I have been doing reactions under some pretty scary set ups. Sure I have used a reflux condeners and distillation apparatus, but I think the scariest set up I have used is the schlenk line. I am constantly paranoid that:
- My reaction vessel will implode because it cant take the vaccum when Im drying under product
- That liquid oxygen will condense in the line and go bang because I have been careless at some stage
The worst reagent I have personally worked with is MOM-Cl because of all the precautions and paperwork before I can use it, not that I really want to use it (sometimes I have no choice).