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Topic: Synthesis method of (4-acetylphenyl) acetate  (Read 1778 times)

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Offline bless87

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Synthesis method of (4-acetylphenyl) acetate
« on: August 29, 2012, 09:34:05 PM »

Hi ^^
my major is organic chemistry : )
Im Beginner !  Help me T.T

how did Synthesis of (4-acetylphenyl) acetate via Friedel-Crafts acylation? (I need specific method T.T)

 

And how did Synthesis of (4-acetylphenyl) acetate via acylation?

If imposible... another easy method?

Offline discodermolide

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Re: Synthesis method of (4-acetylphenyl) acetate
« Reply #1 on: August 29, 2012, 10:08:29 PM »

Hi ^^
my major is organic chemistry : )
Im Beginner !  Help me T.T

how did Synthesis of (4-acetylphenyl) acetate via Friedel-Crafts acylation? (I need specific method T.T)

 

And how did Synthesis of (4-acetylphenyl) acetate via acylation?

If imposible... another easy method?

This looks like a Fries rearrangement to me followed by acylation of the phenol. have a look here:http://en.wikipedia.org/wiki/Fries_rearrangement
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Offline bless87

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Re: Synthesis method of (4-acetylphenyl) acetate
« Reply #2 on: August 29, 2012, 10:22:01 PM »
Thank you for your reply ^^ But, I want specific method Synthesis of (4-acetylphenyl) acetate T.T

Ex) solvent, temperature, etc condition   ..

have a nice day : )

Offline discodermolide

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Re: Synthesis method of (4-acetylphenyl) acetate
« Reply #3 on: August 29, 2012, 10:42:53 PM »
Thank you for your reply ^^ But, I want specific method Synthesis of (4-acetylphenyl) acetate T.T

Ex) solvent, temperature, etc condition   ..

have a nice day : )

I suggest you take a trip to you local Uni library and do a literature search, you will find something there I'm sure.
Use the references on the Wiki page as a starting point. Search Organic Synthesis on-line. Check out some of the other chemistry resources on-line you may well find references there.
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Offline fledarmus

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Re: Synthesis method of (4-acetylphenyl) acetate
« Reply #4 on: August 30, 2012, 08:20:57 AM »
If your university gives you access to SciFinder or Reaccs, they are very helpful for quickly finding synthetic procedures.

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