Hi this is my first post here,

I have the following problem: I want to know how many hydogen bonds (50 kJ each) are needed to fold up a protein at 300K knowing that the protein will be compressed to 10 times its original size after it has been folded.

I have the following entropy equation:

?S= -3/4[R2/r2 + r2/R2]

where R and r are the two radius before and after the fording. So that R=10r

when I solve for the equation i get ?S= 150

and then I have the following equation:

?S= ?H - T?S

Where T is the temperature at which the protein folds.

Puting in my values, I get H=45000 and now I have to divide it by the 50kJ to get the number of H-bonds. This gives me 2250 bonds

I would like to know what are the units I am working with for S and H. I mean, when I first calculated my ?S, is the reslut in J or kJ? And I also wanted to know how you would solve the same problem

Thanks a lot!!!