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Topic: Impregnating PVC with macrocyclic antibiotic valinomycin ISE  (Read 3464 times)

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Offline lbman

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Impregnating PVC with macrocyclic antibiotic valinomycin ISE
« on: February 11, 2013, 06:40:30 PM »
I'm building an ISE as an honors program project for my general chemistry class. I need to impregnate a thin slit of PVC with macrocyclic antibiotic valinomycin. I have no idea how to do so. Any help in the comments or some links with information (I tried looking, couldn't find anything on it, but i don't really know where to look) would be much appreciated. Thank you very much :)

Offline Arkcon

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Re: Impregnating PVC with macrocyclic antibiotic valinomycin ISE
« Reply #1 on: February 11, 2013, 07:47:56 PM »
Hmmm ... tricky.  OK, what is your application:  do you intend to make some sort of bacteriocidal plastic surface, or are you trying to create a thin film to work as some sort of ion gateway?  It might help with your search.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline lbman

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Re: Impregnating PVC with macrocyclic antibiotic valinomycin ISE
« Reply #2 on: February 12, 2013, 01:35:58 AM »
Thin film for ion gateway. Its for a potassium ion selective electrode.

Offline Arkcon

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Re: Impregnating PVC with macrocyclic antibiotic valinomycin ISE
« Reply #3 on: February 12, 2013, 10:44:33 AM »
Thin film for ion gateway. Its for a potassium ion selective electrode.

Awesome.  You're making one of these:  http://en.wikipedia.org/wiki/Potassium_selective_electrode  Check out the reference on that page, it contains further references to the membranes themselves, and how they're made.  Pretty exciting, I would have expected the exothermic polymerization of PVC would damage the biomolecule.  They must have worked it out somehow.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

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