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Topic: Ziconotide (or MVIIA conotoxin) synthesis  (Read 20362 times)

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Offline discodermolide

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #30 on: February 10, 2013, 08:06:28 PM »
Here is the molecule expanded into the amino acids in the chains.
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Offline discodermolide

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #31 on: February 10, 2013, 08:08:19 PM »
as a smiles string!
[H]N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(NCC1=O)=O)=O)NC2=O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCCN)C(NCC(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC3=O)=O)=O)=O)NC([C@H](CO)N1)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CSSC[C@@H](C(O)=O)NC([C@H](CCCCN)N3)=O)=O)CC(O)=O)=O)CC4=CC=C(O)C=C4)=O)CCSC)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O
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Offline nick123

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #32 on: February 10, 2013, 08:18:52 PM »
You are the best!!! I have now found a path...!!!

Thank you with all my heart!!!

And the member Arkcon of course but your help was crucial!

Offline Babcock_Hall

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #33 on: February 11, 2013, 09:59:59 AM »
Just to be clear, are you looking for the chemical synthesis of this polypeptide, or are you looking for its biosynthesis (how it is synthesized in a living organism)?

Offline nick123

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #34 on: February 23, 2013, 02:06:09 AM »
Both of them!!!

Offline nick123

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #35 on: February 23, 2013, 01:13:50 PM »
Does anybody knows whats the ziconotide iupac name?? Does peptide have iupac name?

Offline discodermolide

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #36 on: February 23, 2013, 02:09:56 PM »
This one does not have an IUPAC name.
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Offline nick123

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #37 on: February 23, 2013, 05:39:09 PM »
Thannk you! :)

Offline sjb

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #38 on: February 23, 2013, 07:33:44 PM »
This one does not have an IUPAC name.

Eh? Of course it does, admittedly it'll be very complex here, but why do you feel it has no name?

Offline discodermolide

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Re: Ziconotide (or MVIIA conotoxin) synthesis
« Reply #39 on: February 23, 2013, 09:16:36 PM »
You can find this molecule on quite a few "chemical" sites, under the heading IUPAC name is either blank or a ? Even ChemSpider didn't give me one.
I would not care to work out the longest chain here.
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