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Topic: anyone know the pKa of pyroglutamaic acid  (Read 4933 times)

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Offline pollypui

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anyone know the pKa of pyroglutamaic acid
« on: April 16, 2013, 01:25:43 PM »
anyone know the pKa of pyroglutamaic acid with reference~
thank you very much!!

Offline Arkcon

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #1 on: April 16, 2013, 01:45:36 PM »
Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline pollypui

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #2 on: April 16, 2013, 01:53:36 PM »
Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich


i try it before many time, but i cant found it out:'( :'( :'(

Offline Arkcon

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #3 on: April 16, 2013, 03:13:08 PM »
The first and third results in my Google search, which I linked to above, contained the information you need.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline pollypui

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #4 on: April 16, 2013, 11:50:52 PM »
The first and third results in my Google search, which I linked to above, contained the information you need.

The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(

Offline AWK

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #5 on: April 17, 2013, 01:30:50 AM »
The first pK
Quote
a
(-1.76) is Wikipedia is suspicious
AWK

Offline pollypui

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #6 on: April 17, 2013, 01:48:11 AM »
The first pK
Quote
a
(-1.76) is Wikipedia is suspicious

yes.. so i need the pka with the reference, and i find many hand book.
and none of book have the pKa of pyroglutamaic acid ??? ???
anyone can help me ><

Offline billnotgatez

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #7 on: April 17, 2013, 03:49:52 AM »
Is the information on
http://www.hmdb.ca/metabolites/hmdb00267
relevant

that was the 7th GOOGLE item

Offline Arkcon

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #8 on: April 17, 2013, 06:31:19 AM »
The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline AWK

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #9 on: April 17, 2013, 08:11:38 AM »
http://link.springer.com/article/10.1007%2Fs10953-005-5121-x?LI=true

Journal of Solution Chemistry
July 2005, Volume 34, Issue 7, pp 853-867

Electrical Conductance and Volumetric Studies in Aqueous Solutions of DL-Pyroglutamic Acid
Zoya Orekhova, Yonit Sambira, Emanuel Manzurola, Alexander Apelblat
AWK

Offline pollypui

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #10 on: April 17, 2013, 09:54:00 AM »
The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.

sorry to my impolite..
« Last Edit: April 17, 2013, 12:34:49 PM by pollypui »

Offline AWK

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #11 on: April 17, 2013, 09:59:16 AM »
In my reference pKa1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.
AWK

Offline Corribus

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #12 on: April 17, 2013, 10:47:30 AM »
If you're having so much trouble finding this value, why not just measure it yourself?
What men are poets who can speak of Jupiter if he were like a man, but if he is an immense spinning sphere of methane and ammonia must be silent?  - Richard P. Feynman

Offline pollypui

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #13 on: April 17, 2013, 12:31:45 PM »
In my reference pKa1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.

thank you very much!! :)
is that mean PCA only have one pka?

Offline AWK

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Re: anyone know the pKa of pyroglutamaic acid
« Reply #14 on: April 18, 2013, 03:05:00 AM »
Just look at structural formula
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