April 27, 2024, 07:50:12 AM
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Topic: Stability of acids with hetero atoms  (Read 1160 times)

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Offline PoetryInMotion

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Stability of acids with hetero atoms
« on: April 17, 2013, 01:34:53 PM »
I am supposed to discuss the stability of the following two compounds:



At the first sight, it looks like the α-carbon in the rightmost compound has a quite many electronegative atoms surrounding it, so a first guess is that compound is less stable than the left one. What I do not know, however, is whether any of the compounds are any stable at all. Is there any way of analysing this more systematic? I suppose I am expected to offer a better explanation that in a undergraduate level course :-\
Undergraduate student majoring in chemistry and mathematics. Former IChO participant.

Offline TwistedConf

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Re: Stability of acids with hetero atoms
« Reply #1 on: April 17, 2013, 07:34:25 PM »
Have you tried a literature search?  The second one is like a mini-methionine. What about that could make you question its stability?


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