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Topic: Retrosynthetic Analysis and Synthesis Plan  (Read 1125 times)

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Offline prettyhelix

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Retrosynthetic Analysis and Synthesis Plan
« on: May 02, 2013, 01:08:28 AM »
okay, so I need to conjure up a plan and decide what reagents would work best to make 3,3-dimethyltetrahydro-1H-cyclopenta[e][1,3]dioxpin-7(5H)-one from two different molecules (buta-1,3-diene and furan-2,5-dione). I'm not quite sure how to start this problem and any positive feedback would be kindly appreciated! Thank you :D

here are the molecules I need to use.

Mod edit: img tags added - please do not link to external image hosting websites, upload images or use img tags. Forum rules 3.9. Dan
« Last Edit: May 02, 2013, 02:59:35 AM by Dan »

Offline Dan

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Re: Retrosynthetic Analysis and Synthesis Plan
« Reply #1 on: May 02, 2013, 03:04:47 AM »
You must show you have attempted the question, this is a Forum Rule.

Look at the functional groups and think about how they can be made. The ketal for example, what could it come from?

Since you have been given starting materials, you have to think in both directions (both retrosynthesis and forward synthesis). You've been given a diene and an alkene - looks like you're set up for a very famous named reaction in the first step...
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