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Topic: Conversion of butylscopolamine to scopolamine  (Read 3352 times)

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Offline Memeito

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Conversion of butylscopolamine to scopolamine
« on: September 18, 2013, 05:35:12 AM »
There's a research paper investigating the use of the drug Buscopan for recreational purposes. Butylscopolamine(the active ingredient in Buscopan) doesn't cross the blood-brain barrier but exposed to heat it converts to Scopolamine(about 1% of it). Some possible conversion mechanism are discussed in this paper.
www.icadts2007.org/print/32hyoscinebutylbromide.pdf
What would be a good and reliable  method for converting butylscopolamine to scopolamine?

Offline discodermolide

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Re: Conversion of butylscopolamine to scopolamine
« Reply #1 on: September 18, 2013, 05:47:35 AM »
The Forum rules explicitly say the discussion of drug synthesis is forbidden:

"don't discuss drugs nor explosives synthesis or preparation"

So I fear you will not get many responses to your question except from the moderation.

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Offline curiouscat

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Re: Conversion of butylscopolamine to scopolamine
« Reply #2 on: September 18, 2013, 07:26:25 AM »
 scopolamine reminds me of The Guns of Navarone.

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