April 18, 2024, 12:51:36 AM
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Topic: Olefin metathesis: can it be done with alkynes, and how does the mechanism work?  (Read 2019 times)

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Offline cheesewithwhine

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I found a Grubbs metathesis reaction that is apparently followed by a H2 reduction. Since metathesis reactions involve a 4 member ring transition state, how does it work with alkynes? Some help with the mechanism will be much appreciated!

Offline discodermolide

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Development Chemists do it on Scale, Research Chemists just do it!
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Offline orgopete

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I don't have a contribution here, but the Wikipedia link disco provided raises a question. Do the aromaticity rules apply to the metallocyclobutadiene intermediates shown?
Author of a multi-tiered example based workbook for learning organic chemistry mechanisms.

Offline Dan

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cheesewithwine: This is enyne metathesis (alkyne+alkene), not alkyne metathesis (alkyne+alkyne).
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