March 29, 2024, 07:49:33 AM
Forum Rules: Read This Before Posting


Topic: Solubility of Mono halogenated acetic acids  (Read 3172 times)

0 Members and 1 Guest are viewing this topic.

Offline TheOrganic

  • Regular Member
  • ***
  • Posts: 39
  • Mole Snacks: +5/-3
  • Gender: Male
  • The Organic Chemist
Solubility of Mono halogenated acetic acids
« on: December 30, 2013, 06:18:49 AM »
Hi,

For my paper, I need to do a reaction (determination of enthalpy of solvation) of mono-halogenated acetic acids ( 2-Fluoroacetic acid, 2-Chloroacetic acid, 2-Bromoacetic acid and 2-Iodoacetic acid). I need to get the enthalpy of solvation in some aprotic solvent.

I need any source of information which gives me details about the solubility of these compounds in DMSO, DMF etc. I need an aprotic solvent in which all of these 4 compounds are soluble.

I did an extensive search, but I could not get concrete information. I tried to counter-search, by searching for solvents in which HVZ reaction takes place ( assuming that products of HVZ reactions are often mono-halo caroboxylic acids ).

Will be nice if someone throws some light.

Thanks 

Offline billnotgatez

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 4399
  • Mole Snacks: +223/-62
  • Gender: Male
Re: Solubility of Mono halogenated acetic acids
« Reply #1 on: December 30, 2013, 08:11:08 AM »
We can assume you check these sites (especially the last link)?

Haloacetic acids
http://en.wikipedia.org/wiki/Haloacetic_acids
Chloroacetic acid
http://en.wikipedia.org/wiki/Monochloroacetic_acid
Bromoacetic acid
http://en.wikipedia.org/wiki/Monobromoacetic_acid

http://lxsrv7.oru.edu/~alang/onsc/solubility/allsolvents.php?solute=chloroacetic+acid

That is all I could find quickly with GOOGLE and WIKI
Do not have access to CRC right now
I expect you did the same with greater patience with little result
I thought the WIKI would have references that might help - but it look as not so

« Last Edit: December 30, 2013, 08:49:50 AM by billnotgatez »

Offline TheOrganic

  • Regular Member
  • ***
  • Posts: 39
  • Mole Snacks: +5/-3
  • Gender: Male
  • The Organic Chemist
Re: Solubility of Mono halogenated acetic acids
« Reply #2 on: December 30, 2013, 02:39:02 PM »
We can assume you check these sites (especially the last link)?

Haloacetic acids
http://en.wikipedia.org/wiki/Haloacetic_acids
Chloroacetic acid
http://en.wikipedia.org/wiki/Monochloroacetic_acid
Bromoacetic acid
http://en.wikipedia.org/wiki/Monobromoacetic_acid

http://lxsrv7.oru.edu/~alang/onsc/solubility/allsolvents.php?solute=chloroacetic+acid

That is all I could find quickly with GOOGLE and WIKI
Do not have access to CRC right now
I expect you did the same with greater patience with little result
I thought the WIKI would have references that might help - but it look as not so

Thanks for that. I did check the last link, however, the site does not return any search-results for fluoro,bromo and iodo acetic acid. I need a bona-fide evidence of an aprotic solvent, in which ALL four are soluble.

Further help appreciated.

Offline BobfromNC

  • Regular Member
  • ***
  • Posts: 87
  • Mole Snacks: +14/-1
Re: Solubility of Mono halogenated acetic acids
« Reply #3 on: January 02, 2014, 04:51:09 PM »
I would be surprised if they are not all soluble in DMSO, most every small organic acid I have dealt with was.   It should be easy enough to test this with a small amount in a vial or small test tube.

Sponsored Links