April 25, 2024, 10:48:34 PM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: Question about methylphosphonate.  (Read 1730 times)

0 Members and 1 Guest are viewing this topic.

Offline laura.g.berger

  • Regular Member
  • ***
  • Posts: 23
  • Mole Snacks: +0/-1
Question about methylphosphonate.
« on: December 09, 2013, 11:03:08 AM »
Hi everybody!

Considering the molecule of methylphosphonate, i would like to know what kind of chemical reaction i could do to obtain ethylphosphonate, if is possible.

Thank you!
Logged

Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +405/-70
  • Gender: Male
    • My research history
Re: Question about methylphosphonate.
« Reply #1 on: December 09, 2013, 11:10:27 AM »
Do you require the acid or the diester?
O=P(O)(O)CC or O=P(OCC)(OCC)CC

The usual way is a Grignard reaction with PCl3 followed by alcoholysis and oxidation to give the ester, oxidation to get the acid.
Logged
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Offline orgopete

  • Chemist
  • Sr. Member
  • *
  • Posts: 2636
  • Mole Snacks: +213/-71
    • Curved Arrow Press
Re: Question about methylphosphonate.
« Reply #2 on: December 10, 2013, 01:05:42 AM »
Arbusov
Logged
Author of a multi-tiered example based workbook for learning organic chemistry mechanisms.

Online Babcock_Hall

  • Chemist
  • Sr. Member
  • *
  • Posts: 5610
  • Mole Snacks: +321/-22
Re: Question about methylphosphonate.
« Reply #3 on: December 10, 2013, 09:05:32 AM »
Is this an intellectual exercise, or are you trying to make it?  There are commercial sources.
Logged
Pages: [1]   Go Up
« previous next »
Sponsored Links