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Topic: hydrolysis of methyl tosylate  (Read 2847 times)

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Offline greentea11

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hydrolysis of methyl tosylate
« on: February 01, 2014, 12:34:55 PM »
Using MeO- and MeOH

which hydrolysis mechanism should I be using (Bac2, Bal1, etc)? have only done carbonyl ester hydrolysis, so where does the MeO- attack methyl tosylate?

any help appreciated
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Offline Hunter2

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Re: hydrolysis of methyl tosylate
« Reply #1 on: February 01, 2014, 02:54:00 PM »
It will attack at the sulfur.
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Offline greentea11

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Re: hydrolysis of methyl tosylate
« Reply #2 on: February 02, 2014, 06:58:27 AM »
Is this not the case: a Bal2 mechanism, with the MeO- attacking the methyl group, to form OTs- and MeOMe?
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