I have a very general question, out of pure curiosity:
is it possible to set up an experiment in the NMR sample tube (if the conditions allow us that, by that I mean no gas bubbling, no extreme temperatures, no overly corrosive or reactive substrates or reagents), and follow the reaction in situ from minute to minute by taking proton spectra (the idea is that the sample tube is in the NMR machine all the time)? Of course the quantities of compounds would be such that good spectra can be generated within a single minute or two (i.e. 5-6 scans, no more)?
Would it be possible to plot a 3D spectrum in which first two dimensions would belong to the ordinary 1D spectra, and 3rd dimension would be time? Do you know any software capable to do that?
I'm asking because I'm tired of doing a larger scale procedure in the lab and then running every 10 minutes downstairs to the NMR lab to take new spectra.