I'm doing a protection of secondary amine in thiomorpholine ring, and it's the first time in general I'm doing a protection of an amino group. I've checked in papers if there is some procedure for this particular case, but I wasn't able to find it.
In your opinion, is Boc a good protective group in this case? My substrate is a secondary amine incorporated in the ring, and I'm not sure if classic Boc procedures will work here).
Which molar ratios of substrate vs. Boc2O vs. DMAP should I use in this case (i.e. is there some rule of thumb for molar ratios when it comes to Boc protection)?