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Topic: Practical application for Walden inversion?  (Read 4224 times)

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Offline cinderblock

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Practical application for Walden inversion?
« on: June 05, 2014, 05:37:19 PM »
What is the Walden inversion used for? Making medicine?

And what kind of equipment would you need to do it? Some kind of reactor?

Offline discodermolide

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Re: Practical application for Walden inversion?
« Reply #1 on: June 06, 2014, 12:08:19 AM »
Do you know what the Walden inversion is?
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Offline cinderblock

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Re: Practical application for Walden inversion?
« Reply #2 on: June 12, 2014, 06:51:41 PM »
I've only read about it. And from what I've read, it has to do with switching the enantiomer around the chiral center of a molecule. Sounds interesting in theory, but I wanted to know what its practical uses are.

Offline discodermolide

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Re: Practical application for Walden inversion?
« Reply #3 on: June 13, 2014, 01:47:37 AM »
I've only read about it. And from what I've read, it has to do with switching the enantiomer around the chiral center of a molecule. Sounds interesting in theory, but I wanted to know what its practical uses are.


Yes it it used for that purpose. But it's use depends upon the molecule you are trying to make. Do you have anything particular in mind for the application? Any particular molecule?
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Offline Babcock_Hall

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Re: Practical application for Walden inversion?
« Reply #4 on: June 13, 2014, 09:09:32 AM »
Enzymologists trying to decide whether or not nucleophilic catalysis occurs sometimes make use of the principle behind a Walden inversion.

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