August 11, 2020, 12:10:40 AM
Forum Rules: Read This Before Posting


Topic: Method for purifying pyruvic aldehyde  (Read 2822 times)

0 Members and 1 Guest are viewing this topic.

Offline wseguins

  • Regular Member
  • ***
  • Posts: 17
  • Mole Snacks: +0/-0
Method for purifying pyruvic aldehyde
« on: August 12, 2014, 01:58:08 PM »
Hello guys, I'm trying to do the oxidation of propyleneglycol to pyruvic aldehyde. Already have used calcium hypochlorite and DMSO. However, I have had a lot of trouble to purify and characterize the pyruvic aldehyde. Do you know another methodology of oxidation (cheap) and a way to purify my product?
Thank you!

Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +404/-70
  • Gender: Male
    • My research history
Re: Method for purifying pyruvic aldehyde
« Reply #1 on: August 12, 2014, 02:00:22 PM »
Try bleach/Tempo in dichloromethane/water with good stirring.
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Offline wseguins

  • Regular Member
  • ***
  • Posts: 17
  • Mole Snacks: +0/-0
Re: Method for purifying pyruvic aldehyde
« Reply #2 on: August 12, 2014, 02:36:44 PM »
Try bleach/Tempo in dichloromethane/water with good stirring.


I was the oxidation of n-propanol and iso-propanol hypochlorite. I Had good results in the oxidation of propylene using DMSO. The problem is the purification of pyruvic aldehyde, because I don’t find methodologies of purification. I found a methodology that utilizes sodium bisulfite, however the DMSO prevents the formation of crystals.

Offline discodermolide

  • Chemist
  • Sr. Member
  • *
  • Posts: 5038
  • Mole Snacks: +404/-70
  • Gender: Male
    • My research history
Re: Method for purifying pyruvic aldehyde
« Reply #3 on: August 12, 2014, 02:42:58 PM »
That's why I suggested a different systen for the oxidation. DMSO is quite difficult to remove.
Development Chemists do it on Scale, Research Chemists just do it!
My Research History

Offline wseguins

  • Regular Member
  • ***
  • Posts: 17
  • Mole Snacks: +0/-0
Re: Method for purifying pyruvic aldehyde
« Reply #4 on: August 12, 2014, 02:55:53 PM »
That's why I suggested a different systen for the oxidation. DMSO is quite difficult to remove.

You have every reason.  :'( :'( :'(

Sponsored Links