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Topic: What is the maximum % of Minoxidil can i make in a 100ml of DMSO?  (Read 4753 times)

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Offline eldarlmari

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Noob needs some help here.

I would like to make a DIY minoxidil solution for my hair.

I've got 1kg of 99% Minoxidil powder sitting@home along with 16 oz of 99% DMSO.

For those of you familiar with topical Minoxidil as a hair loss treatment, you wil know what most of the strength out there are 2%-5%, with the highest being 15%, which are mainy based on several co-solvents- namely ethanol, PG and distilled H2O.

I would like to know what is the maximum amount of minoxidil that I can add into the 100ml solution of DMSO to ensure total solubility and if gentle heating is safe.

Thanks alot to those who can answer my question.

Chemical Information:

Molecular Weight (MW)   209.25
Formula   
C9H15N5O
CAS No.   38304-91-5
Storage   3 years -20℃Powder
6 months-80℃in DMSO
Synonyms   
Solubility (25°C) *   In vitro   DMSO    0.25 mg/mL (1 mM)
Water    <1 mg/mL (<1 mM)
Ethanol    <1 mg/mL (<1 mM)

Offline Borek

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Re: What is the maximum % of Minoxidil can i make in a 100ml of DMSO?
« Reply #1 on: August 29, 2014, 02:54:17 AM »
Please read the forum rules:

Due to their potential health hazards, we will also not help you prepare your own medicines or cosmetics.

Topic locked.
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Offline Arkcon

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Re: What is the maximum % of Minoxidil can i make in a 100ml of DMSO?
« Reply #2 on: August 29, 2014, 06:11:14 AM »
Please trouble yourself to remember that minoxidil is vasodilating anti-hypertensive, that happened to have the side effect of promoting hair growth.  You should be able to infer that its probably not safe to make "the strongest possible solution" and then apply it, you might absorb a dangerous dose.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

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