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Topic: Help with synthesis  (Read 1529 times)

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Offline muffins

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Help with synthesis
« on: February 14, 2015, 06:22:52 PM »
Hello, I can't figure out for the life of me how to solve this.
Since Br is only a weak deactivating sub, it should direct towards ortho/para and not meta. (at least that's what we've been taught).
I can't think of any mild/strong deactivating sub that can be substituted into an ethyl group (which thereafter a Br would be added to using radiation)
Please somebody show me the light.
Thanks
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Offline Dan

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Re: Help with synthesis
« Reply #1 on: February 14, 2015, 07:10:33 PM »
What meta directors do you know?
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Offline OrgXemProf

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Re: Help with synthesis
« Reply #2 on: February 17, 2015, 09:41:33 AM »
How 'bout a meta-directing, electron-withdrawing group that (eventually) can be reduced, either directly or indirectly, to CH2CH3?
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