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Topic: Organic synthesis terminology  (Read 1662 times)

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Offline Rutherford

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Organic synthesis terminology
« on: February 24, 2015, 10:31:37 AM »
I have some trouble understanding the meaning of the one-group and two-group disconnections. Why is the disconnection of an amide to acyl halide and amine a one-group, but the disconnection of and beta hydroxy amine (to epoxide and amine) a two group disconneciton?

Offline kriggy

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Re: Organic synthesis terminology
« Reply #1 on: February 24, 2015, 03:31:10 PM »
Im not sure but I think the difference is that you have one functional group in amide but two in the betha-hydroxy amine (hydroxy and amino group). I checked the Warren book but its not clear to me either

Offline Rutherford

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Re: Organic synthesis terminology
« Reply #2 on: February 25, 2015, 09:29:50 AM »
Yeah, I can't find a straightforward definition.

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