I currently have my product stirring in water and I am sure my free amine is probably coordinated to TFA. I was wondering, what is the best way to make the HCl salt and crash my stuff out? I am planning to evaporate the water (Product is very soluble so work up will be a headache), the reconstitute in 4.0M HCl dioxane and then crash the salt out?
Any suggestions? Unfortunately the need for water to make the compound seems to be necessary so I can not avoid having it there.