Imines are stable under anhydrous conditions or in anhydrous organic solvents. Contrary, imines are easily hydrolyzed to the initial amine and the carbonyl compound, in aqueous medium. Imine hydrolysis is fast under acidic or Lewis acid catalysis. Under neutral or alkaline conditions, imine hydrolysis is relatively slow.
In other words, the nature of “hydrocarbyl” radical does not play a very important role towards imine hydrolysis. Anyway, due to steric hindrance ketone imines are a little less unstable than aldehyde imines, towards hydrolysis. Also, long chain and fatty hydrocarbyl imines that are hydrophobic, are relatively more stable than short chain and hydrophilic hydrocarbyl imines, towards hydrolysis.