AKRON or current moderator.
My second post has been merged and hidden with my first post! If you want to merge my questions please make my second question visible - it is more interesting.
I do not mind you merging the two posts but let my second question show, not the simpler first one – I understand the answers to that one.
My comment does not “come out of nowhere”, the problem of T4 to T3 conversion is a chemical process which is organic in nature. The problem is not with the conversion itself, I understand that metabolism, I have studied the literature, it is whether or not the source material (T4) can degenerate within the blood serum before it hits a peripheral organ – usually the liver where the conversion takes place.
Not wanting to put a fine point on this, the drug which is almost universally prescribed for the low thyroid hormone state JUST DOES NOT WORK! Someone has to find out why, and fix the problem, or at least point out where the problem is occurring during the manufacture of this drug.
So please, let my second question show, maybe there is someone out there who has some ideas. My education is in physics and I had thyroid cancer, it is very hard for me to hack through the chemical pathways, but I am trying. Perhaps there is an organic chemist out there with the same problem or an interest in the subject who could give me some pointers as to which processes I should examine to get me closer to a solution.