Im not sure if it belongs into eduation or not so feel free to move it if you think so.
Well, im finishing my masters and want to get PhD. My "German pathway" is not going well for various reasons so I have now two options:
a) stay at my uni, and continue working on what I am doing now - heterocyclic compounds. Pros: I already know the chemistry (some of it) and have some experience with those compounds. Cons: Well, im not sure if I want to synthesise biological active compounds in academia.
b) stay at my uni, and do something else - my PI told me he wants to do some total synthesis of codeine. Pros: learning lots of new reactions, its morphine-like compound so its kinda cool. Cons: Im not sure if I am patient enough to work on something like that, I tend to lose focus when working long on same thign. Also its already done by someone else and Im not sure if its worth even doing.
c) go to other uni, and apply for PhD there. Im going to contact a professor developing methods for stereoselective synthesis and has free spot in a lab.
pros: more prestigious university, closer to home, very interesting work that someone might even use cons: totaly new field where I dont have any experience or knowledge whatsoever and also changing PI for third time.
Those are basicaly my options. Im not trying to make you decide it for me but I would like to hear your experiences. Did any one you completely change the area of chemistry they work in? How did it go?