[sakib shahriar]

How Do I produce Nucleophile Water molecule? Any particular catalyst or chemicals that can be used? Thank you!

[OCSaviour]

We are not supposed to give away direct answers. Here's a hint: Please read the first part of your question, again.

[sakib shahriar]

This is not academic related or part of any kind of homework. The thing is - I came across this term few days in an article and yet after searching extensively on the web, couldn't find any appropriate answer. I would highly appreciate if you could further help me.

[Borek]

You can't "produce nucleophile water molecule". All water molecules are identical, and they are all nucleophiles in exactly the same way.

[Babcock_Hall]

Is this what you are getting at?  Water is a nucleophile in many enzymatic reactions (as well as non enzymatic ones).  It is generally thought to be a poor nucleophile.  What could an enzyme or other catalyst do to make it a better  nucleophile?

[sakib shahriar]

How do I increase the nucleophilic characteristic of water? Any specific way?

[Babcock_Hall]

Unfortunately, you have asked a question that doesn't make any sense.  Please go back and reread our replies, and then see if you can reformulate your question.