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Topic: MOM chloride  (Read 3452 times)

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Offline phth

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MOM chloride
« on: June 19, 2016, 08:28:25 PM »
Has anyone handled this chemical?  Storage conditions? Is vacuum distillation a bad idea?

Offline Guitarmaniac86

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Re: MOM chloride
« Reply #1 on: June 20, 2016, 01:38:12 AM »
Store it at 2 - 8 degrees C (so in the fridge).

When I use it, I place it in a clamp stand so it cant fall over in the fumehood. I use needles to take it up and add it to my flask dropwise.

Any needles, syringes, glassware etc, is left in NaOH solution overnight.

I wouldnt use vacuum distillation only because its nasty carcinogenic stuff. After work up, I will use a rotary evaporator but I would never distill MOM-Cl before use.
Don't believe atoms, they make up everything!

Offline TheUnassuming

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Re: MOM chloride
« Reply #2 on: June 20, 2016, 03:18:05 PM »
As long as the bottle is really old/misused and your reaction isn't extremely sensitive, you shouldn't need to repurify MOMCl.   

Its a membrane permeable alkylating agent, so keep it in the fume hood, don't sniff it, wear gloves, and you will be fine.
When in doubt, avoid the Stille coupling.

Offline rolnor

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Re: MOM chloride
« Reply #3 on: August 07, 2016, 06:36:10 AM »
I beleive it is listed as carcinogenic but MOMBr is not?

Offline rolnor

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Re: MOM chloride
« Reply #4 on: August 22, 2016, 08:19:49 AM »
Also, is not the carcinogenic properties coming from the prescense och some bis-chloromethylether wich is formed from formaldehyde and hydrogen chloride in the synthesis?

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