My research team and I are trying to synthesise a new compound, and one of the steps involves an SN2 reaction with theophylline as our nucleophile:
Our hypothesis is that since Br is a good leaving group, it will be displaced by the N-H from the imidazole ring of theophylline. However, we're still not sure if theophylline is a good nucleophile.
I wanted to ask if this reaction is feasible, and if it is, what sort of catalysts and conditions do we need to prepare to carry out this reaction? Any papers. journals and references that I could read would also be appreciated.
Thank you in advance.