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Topic: suzuki coupling  (Read 1647 times)

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Offline GinaTageldin

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suzuki coupling
« on: May 01, 2017, 08:53:38 AM »
please i need your help
i want to perform suzuki coupling reaction with a simple or mild conditions (catalysts) specially most of catalysts are not found in my lab as Pd(dppf)2Cl2 . So, i need your suggestions to do this with available reagents.
could i use pd acetate and tri phenyl phosphine?
if available i need a paper with the simplified procedure and overcome the purity issue of compounds
Thank you
« Last Edit: May 01, 2017, 09:34:02 AM by GinaTageldin »

Offline hypervalent_iodine

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Re: suzuki coupling
« Reply #1 on: May 03, 2017, 01:56:17 AM »
please i need your help
i want to perform suzuki coupling reaction with a simple or mild conditions (catalysts) specially most of catalysts are not found in my lab as Pd(dppf)2Cl2 . So, i need your suggestions to do this with available reagents.
could i use pd acetate and tri phenyl phosphine?
if available i need a paper with the simplified procedure and overcome the purity issue of compounds
Thank you

It is possible with that Pd catalyst, but it depends on your substrates. Your purity issues could be problematic, though. Why can't you purify your starting reagent?

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