October 01, 2020, 02:28:47 AM
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Topic: Stable and radioactive Isotope Labelling  (Read 1974 times)

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Offline veroconnan

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Stable and radioactive Isotope Labelling
« on: April 25, 2017, 11:00:30 AM »
I'm confused about carbon numbering with isotopes:

[1-13C] Phenylalanine is labelled at the carboxyl end (carbon #1)
http://www.sigmaaldrich.com/catalog/product/aldrich/490091?lang=en&region=US

The radioactive [4-3H] Phenylalanine is tritiated on the phenyl ring (which I would have thought would be carbon #7, not carbon #4...) 
http://www.chemicalbook.com/ProductChemicalPropertiesCB4372040_EN.htm

Why aren't the carbons numbered the same way between these two phenylalanine forms? 
For one, the carbon numbering begins at the carboxyl end and for the other, it begins where the ring connects.

Am I going crazy?!

Offline Arkcon

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Re: Stable and radioactive Isotope Labelling
« Reply #1 on: June 11, 2017, 06:54:58 AM »
Funny thing, nomenclature.  Maybe our experts can help?
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

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