August 18, 2019, 05:20:51 AM
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Topic: Epimerisation of N-sulfinyl imine  (Read 868 times)

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Offline mattk92

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Epimerisation of N-sulfinyl imine
« on: February 13, 2018, 04:28:36 PM »
I've got a N-sulfinyl tBu imine and am trying to epimerise the alpha centre. There is a cis-dioxolane at the moment but I'm after the trans. Anyone got any ideas?
I've tried DBU with some success but methoxide, NaHMDS seem to degrade the material

Online rolnor

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Re: Epimerisation of N-sulfinyl imine
« Reply #1 on: February 13, 2018, 09:00:44 PM »
Maybe LDA?

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