[sasol]

Recently I have found on ebay interesting H217O2  imaging contrast agent for NMR. Its isotope O-17 which provide high contrast in NMR analysis now im asking if anyone tries to use it as imaging agent with NMR ? Because its seems to be highly expensive one seller on ebay selling it for 1200usd for 100mg.

[Hacktacular]

Hi Sasol,

I'm no NMR guru but I'd expect it'd be used more for the preparation of compounds as a way to identify any oxygen atoms that might be present (other than inference and tedious guess and checking), so it might just find use as a reactant.  Another potential use might be in tracking metabolic pathways; ICP-MS for example can resolve atomic mass to four decimal places for example which allows for specific isotopes to be identified, having a O-17 might be useful for this kind of application (whether the hydrogen peroxide would again be used as a reactant for something more friendly to people though I could only guess).

[sasol]

Hi Hacktacular

Thank you for your reply.

Interesting very usefull application.  There is also O-18 - H2O2 posted recently.
does O-18 has same properties? Because its way more affordable

Thank You !

[crawlingmcedge]

I hope no one is actually thinking about seriously buying isotopes off a Slovenian seller on ebay. Anyone doing this actually deserves to be scammed for sheer stupidity.

I suspect 18 Oxygen is more used for Mass spec studies since it is Spin 0 and thus NMR silent.

17 O is spin 5/2 and would be NMR active for quadrupolar NMR.

[Babcock_Hall]

Many years ago, I used H₂O¹⁷ in pulsed EPR experiments.  It was difficult to get water that was 50% O-17.  Also hydrogen peroxide solutions are not indefinitely stable. 

[Irlanur]

anyone tries to use it as imaging agent with NMR ?

I have absolutely no clue what you mean. What do you want to do?