April 21, 2019, 04:29:44 AM
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Topic: DEAROMATIZATION OF 5 MEMBERED HETEROCYCLES  (Read 382 times)

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Offline GeorgiaMJ

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DEAROMATIZATION OF 5 MEMBERED HETEROCYCLES
« on: February 06, 2019, 07:33:23 AM »
Hello,
I have trouble finding information about the dearomatization of of 5 membered heterocycles. I know the ways of dearomatization like radical, enzymatic, hydrogenation etc but I cant really find lots of dearomatization reactions. If someone could help me I would be greatful for ever ;D

Offline chenbeier

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Re: DEAROMATIZATION OF 5 MEMBERED HETEROCYCLES
« Reply #1 on: February 06, 2019, 07:48:14 AM »
You have to destroy the 4n+2 Pi electron system, some how. Means removing double bonds.

Offline wildfyr

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Re: DEAROMATIZATION OF 5 MEMBERED HETEROCYCLES
« Reply #2 on: February 06, 2019, 09:03:02 AM »
Someone on here, I think rolnor, posted a great reaction for turning thiophene into a butyl chain.

Offline rolnor

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Re: DEAROMATIZATION OF 5 MEMBERED HETEROCYCLES
« Reply #3 on: February 06, 2019, 10:30:02 AM »
Yes, you use Ranei-Ni.

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