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Topic: reactivity towards grignard  (Read 3803 times)

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Offline sd1234

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reactivity towards grignard
« on: December 09, 2011, 10:14:00 PM »
pl arrange the following in order of increasing reactivity towards rmgx http://postimage.org/image/m26vb8pr9/

in 2nd molecule will steric reasons dominate or inductive effect of o

Offline sd1234

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Re: reactivity towards grignard
« Reply #1 on: December 10, 2011, 12:06:37 AM »
pl arrange the following in order of increasing reactivity towards rmgx http://postimage.org/image/m26vb8pr9/

in 2nd molecule will steric reasons dominate or inductive effect of o

sorry i drew the wrong molecule. its http://postimage.org/image/c56gjd68b/

Offline Telamond

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Re: reactivity towards grignard
« Reply #2 on: December 10, 2011, 04:49:28 AM »
Try drawing the "3D" forms of the two molecules.
Cyclohexanes has the chair and boat, boat being the most stable.
How would the bicyclic one look with an oxygen there? What is its hybridization?

Offline sjb

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Re: reactivity towards grignard
« Reply #3 on: December 10, 2011, 10:21:02 AM »
Try drawing the "3D" forms of the two molecules.
Cyclohexanes has the chair and boat, boat being the most stable.
How would the bicyclic one look with an oxygen there? What is its hybridization?

Erm, isn't the chair form the more stable?

Offline Telamond

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Re: reactivity towards grignard
« Reply #4 on: December 10, 2011, 10:38:14 AM »
Try drawing the "3D" forms of the two molecules.
Cyclohexanes has the chair and boat, boat being the most stable.
How would the bicyclic one look with an oxygen there? What is its hybridization?

Erm, isn't the chair form the more stable?

Bah! >.<! Yes! I thought chair, but I wrote boat. You know, like those times when you say left but walk right?

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