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Topic: 3-Nitroacetophenone preparation  (Read 3130 times)

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Offline joe900

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3-Nitroacetophenone preparation
« on: March 05, 2015, 05:12:09 AM »
why we have to cool the mixture when we are preparing 3-Nitroacetophenone?why we add dropwise to the acetophenone first the sulfuric acid and then nitric acid at the end?

Offline Dan

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Re: 3-Nitroacetophenone preparation
« Reply #1 on: March 05, 2015, 05:38:11 AM »
You must show you have attempted the question, this is a Forum Rule.

What will happen to the temperature if the reaction is not cooled?
Why might this cause a problem?
My research: Google Scholar and Researchgate

Offline joe900

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Re: 3-Nitroacetophenone preparation
« Reply #2 on: March 05, 2015, 06:53:24 AM »
The reaction is highly egzotermic and produces lots of heat, i dont know if it may start a fire, the chemical is instable in big temperature, i dont know if its explosive?

Offline Arkcon

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Re: 3-Nitroacetophenone preparation
« Reply #3 on: March 05, 2015, 08:18:25 AM »
That's a good answer.  But you should also investigate other reasons.  Consider, could it get so hot that the reagent evaporates?  You get no yield from reactant in the air of the hood, instead of the flask.  Could excess heat drive the reaction backwards?  You might want to investigate that.  That is, prove it before you start to claim that.
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline Arkcon

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Re: 3-Nitroacetophenone preparation
« Reply #4 on: March 05, 2015, 08:26:05 AM »
Also look at this thread, a forum regular has asked much the same question over here: http://www.chemicalforums.com/index.php?topic=79245.0
Hey, I'm not judging.  I just like to shoot straight.  I'm a man of science.

Offline joe900

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Re: 3-Nitroacetophenone preparation
« Reply #5 on: March 05, 2015, 09:29:14 AM »
Thank You!! :)

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