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Topic: About nucleophilic aromatic substitution reaction  (Read 1418 times)

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Offline kamiyu

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About nucleophilic aromatic substitution reaction
« on: June 28, 2014, 03:04:08 PM »
You know, you can add some nucleophile such as OH- ion to replace Cl or F atoms on electron deficient ring (SNAr).

I am wondering if it is possible to replace the fluorine with hydrogen atom, i.e. using sodium hydride?

Any experience or knowledge about how to replace the F with H???

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